Do Hair Growth Peptides Help with Hormonal Hair Loss? What You Need to Know

Hair loss is common throughout our lives, but for women over 40, the hormonal changes associated with perimenopause are a prime culprit. The signs may be subtle at first; few extra hairs in your shower drain, a thinner ponytail or top knot, your scalp showing through your hairline or part. But when hair loss becomes more pronounced, the need for a solution feels imminent and deeply personal. Emerging research has shown that hair growth peptides may offer safe, effective and long-term results.

To help you make the best decision for your hair regrowth journey, we’ll explain the science behind hormonal hair loss, why it can accelerate during the perimenopausal years and through menopause, and how the advanced, systemic mechanisms in OMI Hair Growth Peptides can support healthier, fuller hair from the inside out.

Why Hormones Can Cause Hair Loss

Hormonal hair loss, also known as androgenetic alopecia or female pattern hair loss, is caused by imbalances in hormones that disrupt the hair growth cycle. Here are some of the key hormones involved:

Estrogen

During perimenopause, estrogen levels begin to fluctuate; once you reach menopause (when you’ve gone a full year without a menstrual cycle) levels begin to drop off significantly. Because estrogen helps prolong the growth phase of hair follicles, when it’s in short supply, this phase shortens while the resting phase lengthens. This leads to more shedding and slower regrowth, especially on the crown and sides of the scalp.

Testosterone and DHT

While women have much smaller amounts of testosterone than men, its effects become more noticeable during menopause, specifically when Dihydrotestosterone (DHT), a more potent form of testosterone binds to hair follicle receptors. Over time, this causes follicles to shrink and produce thinner, weaker hair.

Cortisol

A decline in estrogen can interfere with the body’s ability to buffer the stress hormone cortisol. A spike in cortisol can suppress the stem cell activity in hair follicles by interfering with cell communication in the dermal papilla, the part of the follicle responsible for growth. This leads to prolonged dormancy and increased shedding.

Thyroid Hormones

When thyroid hormones, which are responsible for regulating metabolism and other critical bodily functions, become dysregulated it can result in hypothyroidism (too much hormone) and hyperthyroidism (too little). Both of these conditions are common in midlife and can disrupt hair cycling, resulting in thinning everywhere across the scalp.

How Perimenopause & Menopause Affects Hair Health

Hormonal shifts during perimenopause and menopause, including reduced estrogen and progesterone as well as increased FSH and LH (reproductive) hormones, significantly impact hair follicles. The hormonal shifts that occur during this transition also causes metabolic changes that contribute to hair thinning in several ways:

• Blood flow to the scalp decreases, weakening follicle function
• Follicles regenerate more slowly due to aging and oxidative stress
• Insulin resistance may trigger excess androgens, increasing hair loss
• Antioxidant activity declines, which makes follicles more vulnerable to damage

Common Symptoms of Menopausal Hair Loss

• Excessive shedding, especially within the first year after menstruation ceases 
• Thinning across the top and sides of the scalp
• Slower regrowth and reduced volume
• Finer texture and increased brittleness

Some women experience these symptoms even when their testosterone levels are normal, indicating that estrogen depletion and aging follicles are likely the main factors.

How is Hormonal Hair Loss Different in Men?

Hormonal hair loss affects men as well, but the pattern and primary causes are different. Here’s why:

DHT Sensitivity

In men, androgenetic alopecia is mainly driven by dihydrotestosterone (DHT), which can trigger hair follicles to shrink when DHT binds to the part of the follicle responsible for hair growth. This results in thinner, shorter hairs and may eventually stop hair growth altogether. Male pattern hair loss typically starts at the temples and crown.

Genetic Influence

Genetics play a larger role in male hair loss, as specific genes determine how sensitive follicles are to DHT. Even men with normal testosterone levels may experience hair loss if their follicles are more responsive to DHT.

Other Contributing Factors

Men are also susceptible to telogen effluvium, a type of shedding caused by stress, illness, or thyroid issues. High cortisol and disrupted thyroid function can extend the resting phase of the hair cycle and reduce hair density.

Andropause and Age-Related Changes

As men age, testosterone levels gradually decline. This process, often called andropause, causes hormonal imbalances that affect hair growth. Reduced testosterone, increased inflammation, and slower follicle regeneration are all contributing factors.

Other Causes of Hormonal Hair Loss

Hormonal hair loss is not limited to menopause or DHT. It can also result from:

• Autoimmune conditions, such as lupus, alopecia areata, and Hashimoto’s thyroiditis
• Polycystic ovary syndrome (PCOS), which raises insulin and androgen levels
• Pregnancy and postpartum changes, due to sudden drops in estrogen
• Chronic stress, which disrupts communication between the brain and hair follicles
• Thyroid disorders, which reduce energy supply to follicles
• High prolactin levels, which interfere with the anagen phase of the hair cycle

Proper testing is essential to uncover underlying causes and determine the best course of action. This may include lab work for TSH, free T3 and T4, ferritin, cortisol, estrogen, testosterone, and inflammatory markers.

How do Hair Growth Peptides Support Hair Growth?

Peptides are short chains of amino acids that send messages to cells. In hair care, they are used to trigger the biological processes needed to support stronger, healthier hair.

• Improve blood flow by increasing nitric oxide production
• Extend the anagen (growth) phase of the follicle
• Stimulate growth factors like VEGF and KGF
• Reduce inflammation in the scalp
• Strengthen follicle structure through enhanced keratin production

Peptides work on a cellular level to encourage regeneration and protect follicles from damage, making them highly effective for both women and men experiencing hair loss.

How OMI Hair Growth Peptides Help

OMI Hair Growth Peptides are designed for women but are equally beneficial for men dealing with hormonal or age-related hair thinning. Key ingredients include:

• IFP Hair Factor™, the key peptide which strengthens hair structure and supports follicle integrity
• Copper, which improves blood flow and reduces inflammation in the scalp
• Zinc, which helps regulate DHT and repair damaged follicles
• B vitamins, which support healthy scalp metabolism and keratin production

OMI Hair Growth Peptides offer a safe and effective hair growth formula that supports long-term hair health without altering hormone levels.

The Benefits of OMI Hair Growth Peptides

OMI Hair Growth Peptides combine clinically supported ingredients that address multiple aspects of hair loss, from follicle aging to structural weakness and nutrient deficiencies.

IFP Hair Factor™

This patented, bioavailable keratin peptide helps:

• Rebuild the hair shaft from within
• Protect against oxidative stress and breakage
• Improve elasticity, shine, and tensile strength

Copper and Zinc

These essential minerals regulate hormone levels, maintain follicle structure, and reduce scalp inflammation. Copper also supports natural pigment production, while zinc contributes to protein synthesis and DNA repair.

B Vitamins

Biotin, pantothenic acid and pyridoxine support:

• Red blood cell formation for improved oxygenation of the scalp
• Keratin and collagen production
• Cellular energy metabolism essential for hair growth

Deficiencies in these nutrients are common in people over 40 and can significantly impair hair health.

Why Peptides Are Especially Helpful After Age 40

What makes OMI Hair Growth Peptides unique is that they provide targeted support without altering hormone levels. As we age, hair follicles become less responsive to growth signals, and more vulnerable to stress and oxidative damage. Peptides help counteract these effects by anchoring the follicle more securely, which helps reduce shedding. They also actually increase the number of follicles that enter the growth phase, while reducing the number that remain in the dormant phase. What’s more, Peptides improve nutrient delivery to the follicles, protect the scalp from inflammation, and enhance the strength and thickness of each individual strand. This is what makes these peptide a smart option for hair regrowth for both women and men.

Supporting Hair Growth with Lifestyle Changes

Like any wellness regimen, adding extra layers of support can help set you up for success. If you take hair growth peptides, be sure to regularly incorporate these healthy habits:

• Reduce stress with meditation, movement, and proper sleep hygiene
• Eat a nutrient-rich diet high in protein, vitamins, and minerals
• Maintain healthy blood sugar and insulin levels by eating smaller, more frequent meals and limiting processed foods
• Avoid hairstyles and heat tools that put excess strain the scalp
• Stay hydrated and support circulation through exercise

The Takeaway

Hormonal hair loss is both complex and emotionally tough, affecting more than just appearance but confidence and well-being.

Peptides offer a safe, science-backed solution that supports your body’s natural ability to heal, restore, and grow stronger hair. OMI Hair Growth Peptides deliver this support through clinically researched ingredients like IFP Hair Factor™ and essential vitamins and minerals.

If you’re tired of seeing more hair on your pillow or brush and want a gentle but powerful approach that works with your body, not against it, OMI Hair Growth Peptides may be the support your follicles need.

Frequently Asked Questions

1. What causes hormonal hair loss in women over 40?

Hormonal hair loss in women over 40 is mainly caused by declining estrogen levels, increased DHT sensitivity, cortisol spikes, and thyroid imbalances that disrupt the hair growth cycle.

2. How are Hair Growth Peptides different from other hair loss treatments?

Hair Growth Peptides use bioavailable keratin peptides and essential nutrients to support hair growth without altering hormones.

3. Can men also benefit from Hair Growth Peptides?

Yes, Hair Growth Peptides support follicle health and regrowth in men experiencing hormonal or age-related hair loss.

4. Are peptides more effective than traditional hair supplements?

Peptides target the root causes of hair thinning by activating growth processes at the cellular level, making them more effective than basic nutritional supplements.

5. What lifestyle changes can enhance the results of hair growth peptides?

Healthy habits like stress reduction, a nutrient-rich diet, and regular exercise can help maximize the benefits of hair growth peptides.